Company Filing History:
Years Active: 1999-2000
Title: Edwin B. George: Innovator in Nerve Growth Research
Introduction
Edwin B. George is a notable inventor based in Baltimore, MD (US). He has made significant contributions to the field of neuroscience, particularly in the area of nerve growth and regeneration. With a total of 2 patents, his work has implications for therapeutic applications in diseases involving neural degeneration.
Latest Patents
One of Edwin B. George's latest patents focuses on stimulating nerve growth with immunophilins. Immunophilin ligands act by binding to receptor proteins, immunophilins, which can regulate the Ca²⁺ dependent phosphatase, calcineurin, and the Ca²⁺ release channel, the ryanodine receptor. These ligands have been discovered to enhance neurite outgrowth in neuronal cell systems by increasing sensitivity to neurotrophic factors. The effects of the immunophilin ligands are detected at subnanomolar concentrations, indicating their potential therapeutic application in diseases involving neural degeneration.
Career Highlights
Edwin B. George is affiliated with The Johns Hopkins University, where he continues to advance research in his field. His innovative work has garnered attention and respect within the scientific community.
Collaborations
He has collaborated with esteemed colleagues such as W. Ernest Lyons and Ted M. Dawson, contributing to the advancement of knowledge in nerve growth and regeneration.
Conclusion
Edwin B. George's contributions to neuroscience through his patents and research at The Johns Hopkins University highlight his role as a key innovator in the field of nerve growth. His work promises to pave the way for new therapeutic strategies in treating neural degeneration.