Company Filing History:
1 out of 111 
1 out of 247 Years Active: 2001
Title: Edward M. Murray: Innovator in Calcium Sensor Protein Research
Introduction
Edward M. Murray is a notable inventor based in Drexel Hill, PA (US). He has made significant contributions to the field of biochemistry, particularly in the study of calcium sensor proteins. With a total of 2 patents, his work has implications for understanding calcium regulation in various organ systems.
Latest Patents
Murray's latest patents focus on nucleic acids encoding human calcium sensor proteins. The first patent details the isolation of a cDNA clone that encodes the calcium sensor found in human placenta. Subsequent Northern blots have confirmed mRNA expression in human parathyroid and kidney tubule cells. The research demonstrates close sequence similarity with the rat Heymann nephritis antigen, a glycoprotein known for its calcium binding ability. Immunohistochemistry has shown a tissue distribution of the calcium sensor protein that aligns with previous descriptions of the Heymann antigen. This research proposes that the identified calcium sensor protein serves as a universal sensor for recognizing variations in extracellular calcium, playing a crucial role in calcium regulation across different organ systems. The calcium sensor protein is classified within the LDL-superfamily of glycoproteins, which primarily function as protein receptors while also possessing important calcium binding capabilities.
Career Highlights
Throughout his career, Edward M. Murray has worked with prominent companies in the pharmaceutical industry, including Rhone-Poulenc Rorer Pharmaceuticals Inc. and Rhone-Poulenc Rorer S.A. His work in these organizations has contributed to advancements in medical research and development.
Collaborations
Murray has collaborated with notable individuals in his field, including Göran Akerström and Claes Juhlin. These partnerships have likely enhanced the scope and impact of his research.
Conclusion
Edward M. Murray's innovative work in the field of calcium sensor proteins has paved the way for further research and understanding of calcium regulation in human health. His contributions are significant in the realm of biochemistry and continue to influence the scientific community.
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