Edward M Atkinson

Title: Edward M Atkinson: Innovator in Gene Delivery Technologies

Introduction

Edward M Atkinson is a notable inventor based in Indianapolis, IN (US). He has made significant contributions to the field of gene delivery through his innovative methods and compositions. His work primarily focuses on the production of recombinant adeno-associated virus (AAV) vectors, which are essential for gene therapy applications.

Latest Patents

Atkinson holds a patent for "Methods for generating high titer helper-free preparations of released recombinant AAV vectors." This invention provides methods and compositions for producing high titer, substantially purified preparations of recombinant AAV that can be used as vectors for gene delivery. The AAV producer cells typically comprise one or more AAV packaging genes, an AAV vector with a heterologous transgene of interest, and a helper virus such as an adenovirus. The AAV vector preparations produced are generally replication incompetent but capable of mediating the delivery of a transgene of interest, such as a therapeutic gene, to various tissues and cells. The invention also ensures that the AAV vector preparations are substantially free of helper virus and other contaminants.

Career Highlights

Atkinson's career is marked by his role at Targeted Genetics Corporation, where he has contributed to advancing gene therapy technologies. His innovative approaches have paved the way for more effective gene delivery systems, enhancing the potential for therapeutic applications.

Collaborations

Atkinson has collaborated with notable colleagues, including Ian L Aranha and Victor Fung. These partnerships have further enriched his research and development efforts in the field of gene therapy.

Conclusion

Edward M Atkinson's contributions to the field of gene delivery through his innovative patent demonstrate his commitment to advancing medical science. His work continues to influence the development of effective gene therapy solutions.