Company Filing History:
Years Active: 1998-2001
Title: The Innovations of Edward G. Spack
Introduction
Edward G. Spack is a notable inventor based in Mountain View, California. He has made significant contributions to the field of immunology, particularly in the monitoring of T cell reactivity. With a total of two patents to his name, his work has implications for both research and clinical applications.
Latest Patents
One of Edward G. Spack's latest patents is a method for monitoring T cell reactivity. This invention provides a highly sensitive assay for the detection of T-cells reactive to an antigen by detecting a soluble factor whose secretion is induced by stimulation of the T-cell by the antigen. The assay includes an antigen-driven proliferation of specific T cells prior to restimulation with irradiated antigen presenting cells (APCs) and antigen. In exemplary embodiments, the assay is used to enhance the detection limits of human peripheral blood mononuclear cells (PBMCs) secreting interferon-γ (IFN-γ) and interleukin-2 (IL-2). The assay can be performed on previously frozen PBMCs, providing greater convenience in sample processing, multiple use of a single sample as an internal standard, and simultaneous analysis of samples collected at different time points.
Career Highlights
Edward G. Spack has been instrumental in advancing methodologies that improve the detection and analysis of immune responses. His work at Anergen, Inc. has positioned him as a key figure in the development of innovative assays that have the potential to enhance patient care and research outcomes.
Collaborations
Some of his notable coworkers include Nancy G. Wehner and Michael A. McCutcheon. Their collaborative efforts have contributed to the success of the projects they have undertaken together.
Conclusion
Edward G. Spack's contributions to the field of immunology through his innovative patents demonstrate his commitment to advancing scientific knowledge and improving healthcare solutions. His work continues to influence the landscape of T cell monitoring and analysis.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.