Edward G Niles

Title: Edward G Niles: Innovator in Genetic Engineering

Introduction

Edward G Niles is a prominent inventor based in Amherst, NY (US). He has made significant contributions to the field of genetic engineering, particularly in the area of gene expression in eukaryotic cells. His innovative work has led to the development of a unique transient expression system that utilizes bacteriophage RNA polymerase.

Latest Patents

Niles holds a patent for "Prokaryotic expression in eukaryotic cells." This patent describes a transient expression system that employs bacteriophage RNA polymerase in conjunction with a DNA-based cytoplasmic virus. This system facilitates the expression of a foreign gene within the cytoplasm of a eukaryotic cell. The method involves incorporating a DNA-based cytoplasmic virus and a suitable carrier that includes a gene for RNA polymerase, which is foreign to both the carrier and the cells. Additionally, it includes a functional cistron with a foreign gene flanked by a promoter sequence recognized by the RNA polymerase. Niles has 1 patent to his name.

Career Highlights

Edward G Niles is affiliated with The State University of New York, where he has contributed to various research initiatives. His work has been instrumental in advancing the understanding of gene expression mechanisms in eukaryotic systems.

Collaborations

Niles has collaborated with notable scientists in his field, including Bernard Moss and F William Studier. These collaborations have further enriched his research and contributed to the advancement of genetic engineering.

Conclusion

Edward G Niles is a key figure in the realm of genetic engineering, with a focus on innovative methods for gene expression in eukaryotic cells. His contributions continue to influence the field and pave the way for future advancements.