Edward Christopher Hulme

Title: Edward Christopher Hulme: Innovator in Membrane Protein Stability

Introduction

Edward Christopher Hulme is a notable inventor based in London, GB. He has made significant contributions to the field of biochemistry, particularly in the area of membrane proteins. His innovative work has led to the development of methods that enhance the stability of these crucial proteins.

Latest Patents

Hulme holds a patent for "Mutant proteins and methods for selecting them." This patent describes a method for selecting a membrane protein with increased stability. The method involves providing one or more mutants of a parent membrane protein in a membrane-containing composition. These mutants are exposed to a membrane destabilizing agent, which effectively destabilizes the parent membrane protein in situ. The process includes determining whether the mutant membrane proteins exhibit increased stability compared to the parent protein and selecting those with enhanced stability.

Career Highlights

Edward Christopher Hulme is associated with Heptares Therapeutics Limited, where he applies his expertise in protein stability. His work is pivotal in advancing therapeutic applications that rely on stable membrane proteins.

Collaborations

Hulme has collaborated with notable scientists such as Malcolm Peter Weir and Richard Henderson. These partnerships have further enriched his research and contributed to the success of his innovations.

Conclusion

Edward Christopher Hulme's contributions to the field of membrane protein stability exemplify the impact of innovative thinking in biochemistry. His patent and collaborations highlight the importance of research in developing more effective therapeutic solutions.