Company Filing History:
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Years Active: 2016
Title: The Innovations of Edward A. Fox
Introduction
Edward A. Fox is a notable inventor based in Boston, MA (US). He has made significant contributions to the field of cancer research through his innovative work. His expertise lies in the diagnosis of cancer susceptibilities and defective DNA repair mechanisms.
Latest Patents
Edward A. Fox holds a patent for "Methods and compositions for the diagnosis of cancer susceptibilities and defective DNA repair mechanisms and treatment thereof." This patent provides methods and compositions for diagnosing cancer susceptibilities and defective DNA repair mechanisms. Among the sequences provided, the FANCD2 gene has been identified, along with probes and primers for screening patients in genetic-based tests. This work is crucial for diagnosing Fanconi Anemia and cancer. The FANCD2 gene can also be targeted in vivo for preparing experimental mouse models to screen new therapeutic agents for treating conditions involving defective DNA repair. The FANCD2 polypeptide has been sequenced and exists in two isoforms, identified as FANCD2-S and the monoubiquinated FANCD-L form. Antibodies, including polyclonal and monoclonal antibodies, have been prepared to distinguish these isoforms and are used in diagnostic tests to determine whether a subject has an intact Fanconi Anemia/BRCA pathway. He has 1 patent to his name.
Career Highlights
Throughout his career, Edward A. Fox has worked with prestigious institutions, including Dana-Farber Cancer Institute Inc. and Oregon Health & Science University. His work has significantly advanced the understanding of cancer and DNA repair mechanisms.
Collaborations
Edward A. Fox has collaborated with esteemed colleagues such as Alan D. D'Andrea and Toshiyasu Taniguchi. Their combined efforts have contributed to groundbreaking research in the field of cancer diagnostics and treatment.
Conclusion
Edward A. Fox's innovative contributions to cancer research and his patent on diagnostic methods highlight his importance in the scientific community. His work continues to pave the way for advancements in cancer treatment and understanding.