Location History:
- Milford, NJ (US) (2001)
- West Milford, NJ (US) (2001)
Company Filing History:
Years Active: 2001
Title: The Innovative Contributions of Dwight E Raff
Introduction
Dwight E Raff is a notable inventor based in Milford, NJ (US), recognized for his significant contributions to the field of pharmaceuticals. With a total of 2 patents, Raff has made strides in developing compounds that have the potential to impact medical treatments.
Latest Patents
Raff's latest patents focus on the synthesis of omapatrilat, a potent inhibitor of angiotensin-converting enzyme (ACE) and neutral endopeptidase (NEP). His first patent details hydantoin intermediates for the synthesis of omapatrilat and methods for producing and using the same. Omapatrilat is currently undergoing large-scale clinical trials as an anti-hypertensive medication. The synthesis process involves using the S-stereoisomer of a compound derived from a novel hydantoin. The hydantoin can be prepared from a monoacetal or via a dinitrile. His second patent also addresses dinitrile intermediates for the synthesis of omapatrilat, emphasizing the use of a racemic mixture that can be prepared from a hydantoin.
Career Highlights
Dwight E Raff has established himself as a key figure in the pharmaceutical industry, particularly through his work at Dixie Chemical Company. His innovative approaches to drug synthesis have garnered attention and respect within the scientific community.
Collaborations
Raff collaborates with Robert G Brown, further enhancing the research and development efforts in their field. Their partnership exemplifies the importance of teamwork in driving innovation.
Conclusion
Dwight E Raff's contributions to the field of pharmaceuticals, particularly through his patents related to omapatrilat, highlight his role as an influential inventor. His work continues to pave the way for advancements in medical treatments.