Duane E Johnson

Title: Duane E Johnson: Innovator in Gene Therapy

Introduction

Duane E Johnson is a notable inventor based in Encinitas, CA (US). He has made significant contributions to the field of gene therapy through his innovative work on cationic amphiphiles. His research focuses on the transport of therapeutic molecules into cells, which has important implications for medical treatments.

Latest Patents

Duane E Johnson holds a patent for "Organ-specific targeting of cationic amphiphile / DNA complexes for gene therapy." This patent describes novel cationic amphiphiles that facilitate the transport of biologically active therapeutic molecules into cells. The amphiphiles are designed with lipophilic groups derived from steroids and cationic groups that are protonatable at physiological pH. The therapeutic compositions developed from this invention can deliver DNA, RNA, and polypeptides into cells, making them valuable for gene therapy and other medical applications.

Career Highlights

Duane E Johnson is associated with Genzyme Corporation, where he has contributed to advancements in gene therapy technologies. His work has been instrumental in developing effective plasmid constructs for clinical conditions complicated by inflammation. His innovative approach to organ-specific targeting through intravenous administration of therapeutic compositions has opened new avenues in gene therapy.

Collaborations

Duane has collaborated with notable colleagues such as Ronald K Scheule and Rebecca G Bagley. Their combined expertise has further enhanced the research and development of therapeutic compositions in the field of gene therapy.

Conclusion

Duane E Johnson's contributions to gene therapy through his innovative patent and work at Genzyme Corporation highlight his role as a significant inventor in the medical field. His research continues to pave the way for advancements in the delivery of therapeutic molecules, ultimately benefiting patients in need of effective treatments.