Company Filing History:
Years Active: 1992-1998
Title: Drzislav Mismer: Innovator in Ciliary Neurotrophic Factor Research
Introduction
Drzislav Mismer is a notable inventor based in Boulder, CO (US). He has made significant contributions to the field of neurobiology, particularly through his work on ciliary neurotrophic factors. With a total of 2 patents, his research has paved the way for advancements in understanding and utilizing these critical proteins.
Latest Patents
Drzislav Mismer's latest patents focus on the purification and application of ciliary neurotrophic factor (CNTF), specifically the sciatic nerve CNTF (SN-CNTF). The SN-CNTF described in his patents is a single protein species that exhibits a remarkable increase in specific activity, exceeding 25,000-fold from crude extract. His patents also provide amino acid data for this SN-CNTF, along with methods for utilizing this data to create SN-CNTF probes and for screening cDNA and genomic libraries. Furthermore, he describes recombinant-DNA methods for producing SN-CNTF and provides nucleic acid sequences encoding both rabbit and human CNTF. A recombinant expression system is also detailed for the production of biologically active CNTF.
Career Highlights
Throughout his career, Drzislav Mismer has worked with prominent companies in the biotechnology sector, including Synergen, Inc. and Amgen Inc. His experience in these organizations has contributed to his expertise in the field and has facilitated his innovative research.
Collaborations
Drzislav has collaborated with esteemed colleagues such as Franklin D Collins and Leu-Fen H Lin. These partnerships have likely enhanced the scope and impact of his research endeavors.
Conclusion
Drzislav Mismer's work in the field of ciliary neurotrophic factors represents a significant advancement in neurobiology. His patents and collaborations reflect his dedication to innovation and research in this vital area.