This inventor holds 1 USPTO granted patent. Top assignee: The United States of America as Represented by the Department of Health. Active years: 1998.
Company Filing History:
Years Active: 1998
Title: The Innovative Contributions of Douglas W. Laske
Introduction
Douglas W. Laske is a notable inventor based in Rockville, MD (US). He has made significant contributions to the field of medical technology, particularly in drug delivery systems. His innovative approach has the potential to enhance treatment options for various medical conditions.
Latest Patents
Douglas W. Laske holds a patent for a method titled "Convection-enhanced drug delivery." This method involves high-flow microinfusion, which provides convection-enhanced delivery of agents into the brain and other solid tissue structures. The technique requires positioning the tip of an infusion catheter within a tissue structure and supplying an agent through the catheter while maintaining a pressure gradient during infusion. Experimental delivery rates of 0.5 to 15.0 µl/min have been utilized, achieving infusion distances greater than 1 cm from the delivery source. This method can be applied to deliver various drugs, protein toxins, antibodies for treatment or imaging, proteins in enzyme replacement therapy, growth factors for neurodegenerative disorders, and even viruses and gene therapy. The infusion catheter developed for this high-flow microinfusion includes elongated slits adjacent to a tapered portion, which are parallel to the catheter's axis and symmetrically spaced around its circumference.
Career Highlights
Douglas W. Laske is associated with the United States of America as represented by the Department of Health. His work focuses on advancing medical technologies that can significantly improve patient outcomes. His innovative methods have the potential to revolutionize how drugs are delivered to patients, particularly in critical areas such as neurology.
Collaborations
Some of his notable coworkers include Richard Hunt Bobo and Paul F. Morrison. Their collaborative efforts have contributed to the development and refinement of innovative medical technologies.
Conclusion
Douglas W. Laske's contributions to the field of drug delivery systems exemplify the impact of innovation in medicine. His patented methods have the potential to enhance treatment efficacy and improve patient care.