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1 out of 19 Years Active: 2003-2017
Title: Douglas Smith: Innovator in Nucleic Acid Technologies
Introduction
Douglas Smith is a prominent inventor based in Gloucester, MA (US). He has made significant contributions to the field of molecular biology, particularly in the development of methods for producing paired tags from nucleic acid sequences. With a total of 6 patents, his work has advanced the understanding and manipulation of genetic material.
Latest Patents
One of Douglas Smith's latest patents focuses on methods for producing a paired tag from a nucleic acid sequence. This innovative method involves creating a paired tag that includes both the 5' end tag and the 3' end tag of the nucleic acid sequence. The nucleic acid sequence in this patent comprises two restriction endonuclease recognition sites that are specific for a restriction endonuclease, which cleaves the nucleic acid sequence distally to these recognition sites. Additionally, the sequence may include recognition sites for a rare cutting restriction endonuclease. The methods outlined in this patent also describe the use of paired tags to characterize nucleic acid sequences, including karyotyping and mapping of genomes. Furthermore, the patent provides a method for identifying nucleic acid sequences that encode at least two interacting proteins.
Career Highlights
Throughout his career, Douglas Smith has worked with notable companies in the biotechnology sector, including Applied Biosystems, LLC and Life Technologies Corporation. His experience in these organizations has allowed him to collaborate on various innovative projects that have pushed the boundaries of genetic research.
Collaborations
Some of Douglas Smith's notable coworkers include Kevin J McKernan and Joel Malek. Their collaborative efforts have contributed to advancements in the field of nucleic acid technologies.
Conclusion
Douglas Smith's work in developing methods for nucleic acid manipulation has had a profound impact on molecular biology. His innovative patents and collaborations with leading companies and professionals in the field continue to shape the future of genetic research.