Location History:
- Weston, MA (US) (2000 - 2002)
- Portland, OR (US) (1994 - 2008)
Company Filing History:
2 out of 505 
2 out of 2,893 
1 out of 199 
Years Active: 1994-2008
Title: The Innovative Contributions of Douglas R. Keene
Introduction
Douglas R. Keene is a distinguished inventor based in Portland, OR, known for his notable contributions to the field of human collagen research. With a total of five patents to his name, his work has significantly advanced the understanding and application of collagen XXII, a novel human collagen.
Latest Patents
One of Douglas R. Keene's latest innovations is centered around "Collagen XXII, a novel human collagen and uses thereof." This patent provides detailed descriptions of isolated nucleic acid molecules, referred to as collagen XXII nucleic acid molecules, which encode for a new type of collagen. The invention includes antisense nucleic acid molecules, recombinant expression vectors containing the collagen XXII nucleic acids, and host cells that have integrated these vectors. Additionally, nonhuman transgenic animals are encompassed in the invention, creating models in which the collagen XXII gene has been either introduced or disrupted. The patent also presents isolated collagen XXII proteins, fusion proteins, antigenic peptides, and anti-collagen XXII antibodies. Furthermore, diagnostic methods leveraging the invention's compositions are described, highlighting the potential applications in medical diagnostics and therapeutics.
Career Highlights
Douglas R. Keene's career has been marked by his association with prominent institutions, including the Oregon Health & Science University and The General Hospital Corporation. His work in these organizations has laid the groundwork for significant advancements in his field, particularly regarding collagen-based therapies and diagnostics.
Collaborations
Throughout his career, Douglas has collaborated with fellow researchers, including Robert E. Burgeson and Gregory P. Lunstrum. These partnerships have enabled him to explore diverse approaches to innovation, enriching his work and expanding the impact of his inventions.
Conclusion
Douglas R. Keene continues to be a pivotal figure in the realm of biomedical innovation, particularly through his work on collagen XXII. His patents not only exemplify the essence of inventive spirit but also have the potential to make substantial contributions to medical science and treatment methodologies. His dedication and collaborative efforts mark him as an influential inventor in the ongoing exploration of human collagen applications.