Company Filing History:
Years Active: 2013-2014
Title: Douglas Edward Prah: Innovator in Magnetic Resonance Imaging
Introduction
Douglas Edward Prah is a notable inventor based in Milwaukee, WI (US), recognized for his contributions to the field of magnetic resonance imaging (MRI). With a total of two patents to his name, Prah has made significant advancements in imaging methodologies that enhance the accuracy and effectiveness of medical diagnostics.
Latest Patents
Prah's latest patents include a groundbreaking methodology for multiparameter perfusion imaging with leakage correction. This innovative approach allows for the simultaneous measurement of dynamic susceptibility contrast (DSC) MRI and dynamic contrast-enhanced (DCE) MRI perfusion and permeability parameters. By utilizing a combination of dual echo and spiral acquisition techniques without the need for contrast agent preload, this method effectively eliminates T1 and T2/T2* leakage effects. As a result, it enables precise measurements of blood volume, blood flow, and vascular permeability, which are crucial for evaluating tumor angiogenesis.
Another significant patent by Prah involves in vivo mitochondrial labeling using positively-charged nitroxide enhanced and gadolinium chelate enhanced magnetic resonance imaging. This system and method facilitate the acquisition of MR imaging data from subjects by administering positively-charged nitroxides or gadolinium chelates for mitochondrial labeling. The resulting images provide enhanced contrast in areas of metabolic and mitotic activity, thereby improving diagnostic capabilities.
Career Highlights
Throughout his career, Douglas Edward Prah has worked with prominent organizations such as Imaging Biometrics, LLC and the Medical College of Wisconsin Research Foundation. His work in these institutions has contributed to the advancement of MRI technologies and their applications in clinical settings.
Collaborations
Prah has collaborated with esteemed colleagues, including Kathleen M. Schmainda and Eric S. Paulson. These partnerships have fostered innovation and have played a vital role in the development of new imaging techniques.
Conclusion
Douglas Edward Prah's contributions to the field of magnetic resonance imaging exemplify his dedication to advancing medical technology. His innovative patents and collaborations have significantly impacted the way imaging is conducted, ultimately enhancing patient care and diagnostic accuracy.