Douglas B Hecker

Title: Innovations of Douglas B Hecker

Introduction

Douglas B Hecker is a notable inventor based in Liberty, MO (US). He has made significant contributions to the field of pharmaceuticals, particularly in the development of innovative drug delivery systems. With a total of 11 patents to his name, Hecker's work has had a substantial impact on the industry.

Latest Patents

One of Hecker's latest patents is a DPI formulation containing sulfoalkyl ether cyclodextrin. This invention provides an inhalable dry powder formulation that includes SAE-CD and an active agent. The formulation is designed for administration via a dry powder inhaler (DPI). The SAE-CD acts as a carrier rather than an absorption enhancer, ensuring that the average particle size is large enough to minimize pulmonary deposition. Upon release from the DPI device, the SAE-CD-containing particles dissociate from the active agent-containing particles in the buccal cavity or throat, allowing the active agent to penetrate deeper into the respiratory tract. The physicochemical and morphological properties of the SAE-CD can be easily modified to optimize interactions between the active agent and the carrier. This innovation allows for the delivery of drugs with various electrostatic charges using DPI technology.

Another significant patent by Hecker involves sulfoalkyl ether cyclodextrin compositions and methods of preparation. This particulate SAE-CD composition boasts a unique combination of physical properties that are not found in existing solid forms of SAE-CD. The composition is tailored for specific uses, offering improved flow and dissolution performance compared to known SAE-CD compositions.

Career Highlights

Hecker's career is marked by his dedication to advancing pharmaceutical technologies. His work at Cydex Pharmaceuticals, Inc. has positioned him as a leader in the field of drug delivery systems. His innovative approaches have led to the development of formulations that enhance the efficacy of various therapeutic agents.

Collaborations

Hecker has collaborated with notable colleagues, including James D Pipkin and Gerold L Mosher. These partnerships have contributed to the successful development of his patented technologies.

Conclusion

Douglas B Hecker's contributions to the field of pharmaceuticals through his innovative patents demonstrate his commitment to improving drug delivery systems. His work continues to influence the industry and pave the way for future advancements.