Company Filing History:
Years Active: 2011
Title: Innovations in Parasite Genome Transformation by Douglas A. Shoue
Introduction
Douglas A. Shoue, a dedicated inventor based in North Liberty, Indiana, has made significant contributions to the field of genetic research. With one patent to his name, Shoue's work focuses on the molecular methods for transforming the genomes of common disease-transmitting parasites, which is crucial for combating diseases such as malaria.
Latest Patents
Shoue holds a patent that presents groundbreaking methods for enhancing the transformation efficiencies of parasite genomes, achieving improvements of up to 100 times compared to conventional approaches. This invention targets non-specifically TTAA-rich sites in the parasite genome, enabling a high saturation of 50% or greater. Additionally, his work introduces a model for functional genome annotation, facilitating the design of compounds that can help control and inhibit diseases brought about by these parasites. Notably, his approach incorporates highly efficient and multi-site integrating transposons, especially piggyBac transposons, which enable random integration into parasite genomes.
Career Highlights
Currently, Douglas A. Shoue is affiliated with the University of Notre Dame du Lac, where he continues to advance research in molecular genetics. His innovative work has the potential to reshape how researchers approach the treatment of diseases spread by parasites, showcasing his commitment to improving public health through scientific inquiry.
Collaborations
Throughout his career, Shoue has collaborated with esteemed colleagues such as John H. Adams and Malcolm J. Fraser. These partnerships have played an instrumental role in fostering an environment of innovation and knowledge sharing, further enhancing the impact of their collective research efforts.
Conclusion
Douglas A. Shoue stands as a prominent figure in the realm of genetic research, particularly in the fight against parasite-borne diseases. With his innovative methodologies and collaborations, he continues to contribute valuable insights and advancements that may lead to significant breakthroughs in public health and disease control. His work inspires future inventors and researchers in the ever-evolving field of genetics.