Doug Paul Dohrman

Title: Doug Paul Dohrman: Innovator in Ethanol Detection

Introduction

Doug Paul Dohrman is a notable inventor based in San Francisco, CA. He has made significant contributions to the field of cellular biology, particularly in understanding the effects of ethanol exposure on cellular proteins. His innovative work has implications for drug screening and treatment development.

Latest Patents

Dohrman holds a patent for the "Detection of cellular exposure to ethanol." This invention focuses on the effects of ethanol on the localization and abundance of specific proteins within cells. The discovery that the catalytic Cα subunit of cAMP-dependent protein kinase (PKA) translocates to the nucleus upon ethanol exposure is a key finding. Additionally, the patent outlines how the δ-subunit of PKC and the ε-subunit of PKC respond to ethanol, providing a basis for assays to detect cellular exposure to ethanol. The invention also includes kits for detecting ethanol exposure, which may contain labeled antibodies that bind specifically to various protein subunits.

Career Highlights

Dohrman is affiliated with the Ernest Gallo Clinic and Research Center, where he conducts his research. His work has contributed to a deeper understanding of cellular responses to ethanol, which is crucial for developing potential treatments for ethanol-related conditions.

Collaborations

He has collaborated with esteemed colleagues such as Ivan Diamond and Adrienne Sue Gordon, further enhancing the impact of his research in the scientific community.

Conclusion

Doug Paul Dohrman's innovative work in detecting cellular exposure to ethanol represents a significant advancement in the field of cellular biology. His contributions have the potential to influence drug development and treatment strategies for ethanol consumption.