Doug C Lee

Title: Innovations by Doug C Lee in Antibody Purification

Introduction

Doug C Lee is an accomplished inventor based in Apex, NC (US). He has made significant contributions to the field of biochemistry, particularly in the purification of antibodies. His innovative methods have the potential to enhance the efficiency and effectiveness of antibody purification processes.

Latest Patents

Doug C Lee holds a patent for a "Chromatographic method for high yield purification and viral." This patent describes an improved process for the purification of antibodies from human plasma or other sources. The method involves suspending antibodies at a pH of 3.8 to 4.5, followed by the addition of caprylic acid and a pH shift to 5.0 to 5.2. This process results in the formation of a precipitate containing contaminating proteins, lipids, and caprylate, which is then removed while the majority of antibodies remain in solution. The method maximizes yield and produces gamma globulin with greater than 99% purity.

Career Highlights

Throughout his career, Doug C Lee has focused on developing innovative solutions in the field of antibody purification. His work has led to advancements that not only improve yield but also ensure the purity of antibodies, which is crucial for various medical applications.

Collaborations

Doug has collaborated with notable colleagues such as Wytold R Lebing and Patricia Alred. These collaborations have contributed to the refinement and success of his innovative purification methods.

Conclusion

Doug C Lee's contributions to antibody purification represent a significant advancement in biochemistry. His patented methods enhance the efficiency and purity of antibody extraction, which is vital for medical research and therapeutic applications.