Company Filing History:
Years Active: 2012-2018
Title: Doris Roth: Innovator in Biochemical Detection Methods
Introduction
Doris Roth is a prominent inventor based in Basel, Switzerland. She has made significant contributions to the field of biochemical detection, particularly in the development of methods for measuring important cellular molecules. With a total of 3 patents, her work has advanced the understanding of signal transduction in biological systems.
Latest Patents
One of her latest patents is titled "Method of detection of cAMP and cGMP via a fluorophore and dequencher complex." This invention relates to an in vitro method for detecting cAMP or cGMP by contacting a mixture with a complex of a tracer and a dequencher. The tracer is a fluorophore covalently linked to a cAMP quencher, and the method involves measuring changes in fluorescence. This innovative approach allows for determining the concentration of cAMP or cGMP in a mixture, assessing receptor activity, and screening ligands for specific receptors.
Another notable patent is the "Generic kinase/phosphatase assay with single readout." This invention provides a generic method for detecting kinase or phosphatase activity. The method includes incubating a sample with a substrate molecule that has a detectable readout and a detection entity that alters the readout of the fluorophore. This technique enables the identification of kinase or phosphatase activity in samples, which is crucial for various biochemical applications.
Career Highlights
Doris Roth has worked with renowned companies such as Hoffmann-La Roche Inc. and F. Hoffmann-La Roche AG. Her experience in these organizations has allowed her to collaborate on groundbreaking research and development projects in the pharmaceutical and biotechnology sectors.
Collaborations
Throughout her career, Doris has collaborated with notable colleagues, including Thilo Enderle and Hugues Matile. These partnerships have contributed to her innovative work and the advancement of biochemical detection methods.
Conclusion
Doris Roth is a distinguished inventor whose contributions to biochemical detection have had a lasting impact on the field. Her innovative patents and collaborations reflect her commitment to advancing scientific knowledge and technology.