Company Filing History:
Years Active: 1984
Title: Doris L Keller: Innovator in Gastric Cytoprotection and Anti-inflammatory Therapies
Introduction
Doris L Keller is a prominent inventor based in Edison, NJ (US). She has made significant contributions to the field of pharmaceuticals, particularly in the development of anti-inflammatory and analgesic therapies. With a total of 2 patents, her work has the potential to improve the quality of life for patients suffering from chronic conditions.
Latest Patents
Keller's latest patents include an innovative anti-inflammatory/analgesic combination that utilizes cyclo-(N-methyl-Ala-Tyr-D-Trp-Lys-Val-Phe) in conjunction with a non-steroidal anti-inflammatory drug (NSAID). This combination has been shown to exhibit much lower gastric lesions or ulcers than those typically associated with NSAIDs, making it clinically useful for long-term therapy in patients with chronic rheumatoid arthritis or osteoarthritis. Another notable patent is for gastric cytoprotection using L-363,586, a somatostatin analog that induces gastric cytoprotection through a mechanism that does not involve the inhibition of gastric acid secretions. This compound has specific therapeutic utilities for conditions such as erosive gastritis, erosive esophagitis, inflammatory bowel disease, and ethanol-induced hemorrhagic gastric erosions.
Career Highlights
Doris L Keller is currently associated with Merck & Company, Inc., where she continues to advance her research and development efforts. Her work has garnered attention for its innovative approach to addressing common gastrointestinal issues associated with traditional anti-inflammatory medications.
Collaborations
Keller has collaborated with notable professionals in her field, including Marvin M Goldenberg, to further enhance her research initiatives and patent developments.
Conclusion
Doris L Keller's contributions to the pharmaceutical industry, particularly in the realm of gastric cytoprotection and anti-inflammatory therapies, highlight her role as an influential inventor. Her innovative patents have the potential to significantly impact patient care and treatment outcomes.