Doreen Chan

Title: Innovations in Anti-Fouling Hydrogel Coatings by Doreen Chan

Introduction

Doreen Chan is an accomplished inventor based in Los Angeles, CA. She has made significant contributions to the field of biomaterials and medical devices through her innovative research. Her work focuses on developing solutions to combat biofouling, which is a critical issue affecting the functionality and longevity of medical devices.

Latest Patents

Doreen Chan holds a patent for her invention titled "Polymer formulations for anti-fouling hydrogel coatings." This invention addresses the challenge of fouling on biomaterials and medical devices caused by proteins and microorganisms. The patent highlights the exploration of polyacrylamides in hydrogel coatings, resulting in the largest library of acrylamide-based copolymer anti-biofouling hydrogels to date, with over 160 combinations. The invention employs a combinatorial approach to facilitate high-throughput screening of platelet adhesion, which is a precursor to thrombosis and a common issue in biofouling.

Career Highlights

Doreen Chan's career is marked by her dedication to advancing medical technology. She has demonstrated the applicability of her top-performing polyacrylamide-based hydrogel through various methods. These include coating affinity-based electrochemical biosensors in vitro in a whole blood assay and utilizing an electrochemical aptamer-based device for real-time monitoring of analytes in an in vivo closed-loop system.

Collaborations

Doreen Chan is affiliated with Leland Stanford Junior University, where she collaborates with other researchers and institutions to further her work in biomaterials and medical devices.

Conclusion

Doreen Chan's innovative work in anti-fouling hydrogel coatings represents a significant advancement in the field of medical technology. Her contributions are poised to enhance the functionality and lifespan of medical devices, addressing a critical challenge in healthcare.