Company Filing History:
Years Active: 2023-2025
Title: Innovations of Dongrong Yi in Ebola Virus Inhibition
Introduction
Dongrong Yi is a notable inventor based in Beijing, China. He has made significant contributions to the field of medical science, particularly in the development of antiviral compounds. With a total of 2 patents, his work focuses on innovative solutions to combat viral infections.
Latest Patents
One of Dongrong Yi's latest patents involves the use of berbamine dihydrochloride in the preparation of an Ebola virus inhibitor. This invention targets the primed glycoprotein of the Ebola virus (EBOV-GPcl) as a site for intervention. Through structure-based virtual screening, he identified berbamine dihydrochloride as an antiviral active compound capable of binding to EBOV-GPcl. The compound has demonstrated a strong inhibition effect on the entry of an Ebola recombinant virus, achieving an impressive half-maximum effect concentration (EC50) of 0.49 μM against EBOV.
Career Highlights
Dongrong Yi is affiliated with the Chinese Academy of Medical Sciences, where he conducts his research and development activities. His work is pivotal in advancing the understanding and treatment of viral infections, particularly in the context of Ebola.
Collaborations
He collaborates with esteemed colleagues such as Shan Cen and Quanjie Li, contributing to a dynamic research environment focused on innovative medical solutions.
Conclusion
Dongrong Yi's contributions to the field of antiviral research, particularly through his patents on berbamine dihydrochloride, highlight his commitment to combating viral infections. His work at the Chinese Academy of Medical Sciences continues to pave the way for future innovations in medical science.