Company Filing History:
Years Active: 1994-2014
Title: Donatella Mannucci: A Pioneer in Vaccine Innovations
Introduction
Donatella Mannucci is an accomplished inventor based in Siena, Italy, known for her significant contributions to the field of vaccine development. With two patents to her name, she has focused her research on innovative approaches to enhance vaccine efficacy and safety. Her work has influenced the landscape of immunization and provided new options for combating infectious diseases.
Latest Patents
One of Mannucci's latest patents revolves around combination vaccines incorporating whole cell pertussis antigens. This invention encompasses vaccines that integrate D-T-Pw-HepB-Hib antigens along with one or more meningococcal conjugate antigens. Noteworthy improvements and variations of these vaccines have been explored, allowing for extemporaneous preparation at the time of use. The process involves mixing two components: the first component contains D, T, wP, and HBsAg antigens, while the second component includes a Hib conjugate and one or more meningococcal conjugates.
Another significant patent details an extraction and purification process for human recombinant gamma interferon (HuIFN-gamma). This method describes the extraction from recombinant host cells producing HuIFN-gamma in an insoluble form. The procedure includes suspending the cells in a buffer solution with a pH range of 6.0 to 8.5 and utilizing chromatographic techniques for purification. This innovative technique yields non-degraded HuIFN-gamma with biological activity and chemical-physical properties similar to those of the native product, ensuring high yield and purity.
Career Highlights
Donatella Mannucci has had a remarkable career, working with prestigious companies such as Novartis AG and Sclavo SpA. Her experience in these organizations has significantly influenced her research direction and encouraged collaborations that further her contributions to vaccine science.
Collaborations
Throughout her career, Mannucci has collaborated with notable colleagues, including Mario Contorni and Otello Protasi. Their teamwork and shared expertise have been instrumental in advancing their research and achieving significant breakthroughs in vaccine development.
Conclusion
Donatella Mannucci exemplifies the spirit of innovation in the field of vaccines, demonstrating a commitment to improving public health through her inventive work. Her patents not only reflect her scientific expertise but also her dedication to addressing critical health challenges. As she continues her research, the impact of her contributions will undoubtedly resonate within the medical community for years to come.