Company Filing History:
3 out of 516 
2 out of 79 
1 out of 2,961 
Years Active: 1984-2003
Title: Innovations and Contributions of Donald R. Senger
Introduction
Donald R. Senger is a notable inventor based in Medfield, MA, who has made significant contributions to the field of medical science. With a total of six patents to his name, Senger's work primarily focuses on methods for inhibiting tumor angiogenesis and developing immunological preparations for therapeutic applications.
Latest Patents
One of Senger's latest patents is a method for inhibiting tumor angiogenesis in a living subject. This invention provides a method that relies on tumor angiogenesis mediated by vascular endothelial growth factor and specified induced integrin cell surface receptors expressed on the endothelial cells of tumor-included and tumor-associated blood vessels. The methodology administers at least one antagonistic preparation effective against specified induced and expressed integrin heterodimers on the endothelial cell surface of living subjects, resulting in effective inhibition of tumor angiogenesis in vivo. Another significant patent is an immunological preparation for concurrent specific binding to spatially exposed regions of vascular permeability factor (VPF) bound in vivo to a tumor-associated blood vessel. This preparation comprises not less than two types of conjugate molecules in admixture for specific binding, with applications in analytical studies, in vivo diagnostic testing, and therapeutic treatments.
Career Highlights
Throughout his career, Senger has worked with prestigious institutions such as Beth Israel Deaconess Medical Center, Inc. and The Beth Israel Hospital Association. His innovative
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