Company Filing History:
Years Active: 2006-2010
Title: Innovations by Donald R Oestreicher
Introduction
Donald R Oestreicher is an accomplished inventor based in Cupertino, CA. He has made significant contributions to the field of biological research through his innovative methods and technologies. With a total of 2 patents, Oestreicher's work focuses on characterizing biological stimuli and their effects on cellular phenotypes.
Latest Patents
One of Oestreicher's latest patents is titled "Characterizing biological stimuli by response curves." This method generates stimulus response curves, such as dose response curves, which illustrate how the phenotype of one or more cells changes in response to varying levels of a stimulus. Each point on the curve represents a quantitative phenotype for the cells at a specific stimulus level, such as a therapeutic dose. The quantitative phenotypes are multivariate representations of the cells, incorporating various features obtained through image analysis. These features may include basic parameters like cell shape, nucleus area, and Golgi texture, as well as biological characterizations derived from these parameters, such as cell cycle state and mitotic index. The stimulus response curves can be compared to classify stimuli and identify subtle differences among related stimuli. To enhance comparison, it is often beneficial to present the response curves in a principal component space.
Career Highlights
Oestreicher is currently employed at Cytokinetics, Inc., where he continues to develop innovative solutions in the field of cellular biology. His work has contributed to advancements in understanding how cells respond to various stimuli, which is crucial for therapeutic applications.
Collaborations
Some of Oestreicher's notable coworkers include Eugeni Vaisberg and Cynthia L Adams. Their collaborative efforts have furthered the research and development of innovative methodologies in biological studies.
Conclusion
Donald R Oestreicher's contributions to the field of biological research through his patents and work at Cytokinetics, Inc. highlight his role as a significant innovator. His methods for characterizing biological stimuli are paving the way for advancements in therapeutic applications and cellular biology.