Donald J Dowbenko

Title: The Innovations of Donald J Dowbenko

Introduction

Donald J Dowbenko is a notable inventor based in San Bruno, CA (US). He has made significant contributions to the field of biotechnology, particularly in the study of PSTPIP polypeptides. With a total of 2 patents, his work has implications for understanding cellular processes and potential therapeutic applications.

Latest Patents

Dowbenko's latest patents focus on tyrosine phosphorylated cleavage furrow-associated proteins (PSTPIPs). This invention concerns new PSTPIP polypeptides that are bound by and dephosphorylated by the PEST family of protein tyrosine phosphatases. The invention specifically addresses native murine PSTPIP polypeptides and their homologues in other mammals, along with their functional derivatives. Additionally, it relates to nucleic acids encoding these proteins, vectors capable of expressing such nucleic acid, and recombinant host cells transformed with this nucleic acid. Methods for inducing the polymerization of actin monomers in eukaryotic cells and assays for identifying antagonists and agonists of the PSTPIP polypeptides are also included in this patent.

Career Highlights

Donald J Dowbenko has had a distinguished career, working at Genentech, Inc., a leading biotechnology company. His research has contributed to advancements in understanding cellular mechanisms and has the potential to influence therapeutic strategies.

Collaborations

One of his notable collaborators is Laurence A Lasky, with whom he has worked on various projects related to his patents.

Conclusion

Donald J Dowbenko's innovative work in the field of biotechnology, particularly with PSTPIP polypeptides, showcases his contributions to science and medicine. His patents reflect a commitment to advancing our understanding of cellular processes and their applications.