Company Filing History:
Years Active: 1990-1994
Title: The Innovative Contributions of Donald B. Harden
Introduction
Donald B. Harden is a notable inventor based in Atlanta, GA (US). He has made significant contributions to the field of chemistry, particularly in the synthesis of novel compounds. With a total of 3 patents to his name, his work has implications in various biological applications.
Latest Patents
Harden's latest patents include a method of preparation of halogenated diazines. This method involves the addition of an organolithium reagent followed by the dehydrogenation of the addition product. The reaction occurs in a single vessel, eliminating the need for isolation of the intermediate. This approach not only reduces the likelihood of side reactions but also enhances the yield of the final product. The substituted halogenodiazines produced are valuable intermediates in the synthesis of unfused heterobicyclic compounds that exhibit biological activity.
Another significant patent by Harden is related to di-substituted phthalazines. Similar to his previous work, this method also utilizes organolithium reagents and emphasizes efficiency and high yield. The two-phase workup conditions are designed to prevent hydrolysis, ensuring the integrity of the substituted halogenodiazine. These compounds are crucial for developing new materials with potential biological applications.
Career Highlights
Donald B. Harden is affiliated with the Georgia State University Research Foundation, Inc. His work has been instrumental in advancing the understanding and application of chemical synthesis techniques. His innovative methods have garnered attention in the scientific community for their efficiency and effectiveness.
Collaborations
Harden has collaborated with notable colleagues such as Lucjan Strekowski and Maria Mokrosz. These partnerships have contributed to the success of his research and the development of his patented methods.
Conclusion
Donald B. Harden's contributions to the field of chemistry through his innovative patents have paved the way for advancements in the synthesis of biologically active compounds. His work continues to influence research and development in this important area.