Company Filing History:
13 out of 85 
5 out of 10 
1 out of 1 
Years Active: 1998-2018
Title: Innovations and Contributions of Dominique Bourel in Monoclonal Antibody Development
Introduction
Dominique Bourel, based in La Madeleine, France, is a prominent figure in the field of biotechnology and immunology. With an impressive portfolio of 21 patents, he has significantly contributed to the development of monoclonal antibodies with enhanced functions. His innovative approaches aim to improve therapeutic outcomes for patients suffering from various conditions, particularly those related to Rh isoimmunization and low-responder diseases.
Latest Patents
Among his latest inventions is a groundbreaking method for obtaining and selecting monoclonal antibodies with enhanced antibody-dependent cellular cytotoxicity (ADCC) function. This innovative approach focuses on antibodies capable of activating type III Fcy receptors, reinforced by a specific glycan structure. Notably, these anti-D antibodies demonstrate potential applications in preventing Rh isoimmunization in Rh-negative individuals, especially in cases of hemolytic disease in newborns and conditions such as idiopathic thrombocytopenic purpura (ITP). Bourel's work on ADCC-optimized antibodies also highlights their therapeutic benefits in treating patients with unique genetic profiles, specifically those exhibiting the CD16 FCGR3A-158F homozygote or FCGR3A-158V/F heterozygote polymorphisms.
Career Highlights
Throughout his career, Dominique Bourel has collaborated with esteemed organizations, including Laboratoire Français du Fractionnement et des Biotechnologies and LFB Biotechnologies. These positions have allowed him to advance his research and innovations within the realm of antibody therapies.
Collaborations
In addition to his individual contributions, Bourel has worked alongside notable colleagues such as Nicolas Bihoreau and Emmanuel Nony. Their collaborations have further enhanced the development of innovative antibody therapies and have played a significant role in advancing the field of biotechnology.
Conclusion
Dominique Bourel stands out as a leading inventor and innovator in the field of monoclonal antibodies. His extensive work in enhancing ADCC functions through novel methodologies has opened new avenues for treating various medical conditions. With a commitment to advancing biotechnological research, Bourel continues to impact the healthcare landscape, improving treatments and outcomes for patients worldwide.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.