This inventor holds 2 USPTO granted patents. Top assignees: Degussa Aktiengesellschaft, Forschungszentrum Juelich Gmbh. Active years: 1993-1994.
Company Filing History:
2 out of 1,694 
2 out of 205 
Years Active: 1993-1994
Title: Doerte Steinke: Innovator in Peptide Amidase Technology
Introduction
Doerte Steinke is a notable inventor based in Aachen, Germany. He has made significant contributions to the field of biochemistry, particularly in the development of peptide amidases. With a total of 2 patents, his work has implications for various applications in peptide synthesis.
Latest Patents
One of Steinke's latest patents is focused on a peptide amidase isolated from the flavedo of citrus fruits, particularly oranges. This enzyme is capable of catalyzing the selective hydrolytic elimination of the free amino group on the C-terminal end of peptide amides without cleaving peptide bonds. The enzyme can accept D-amino acid residues in the C-terminal position, although the hydrolysis rate is significantly slower compared to L-amino acid residues. It is weakly inhibited by serine protease inhibitors and has an optimal pH of 7.5 ± 1.5, with an optimum temperature of 30°C at pH 7.5. The enzyme's isoelectric point is pH 9.5, and it remains stable at pH levels between 6.0 and 9.0. The molecular weight of the purified enzyme is approximately 32,000 ± 3,000 daltons. This peptide amidase is particularly useful in the production of peptides through continuous enzymatic reactions involving N-protected amino acid or peptide alkyl esters with amides of amino acids.
Career Highlights
Throughout his career, Doerte Steinke has worked with prominent organizations such as Forschungszentrum Juelich GmbH and Degussa Aktiengesellschaft. His experience in these institutions has allowed him to refine his expertise in enzymatic processes and peptide synthesis.
Collaborations
Steinke has collaborated with notable colleagues, including Alexander Schwarz and Maria-Regina Kula. These partnerships have contributed to the advancement of his research and innovations in the field.
Conclusion
Doerte Steinke's work in peptide amidase technology showcases his innovative spirit and dedication to advancing biochemistry. His patents and collaborations reflect his significant impact on the field, paving the way for future developments in peptide synthesis.