Ding-Yi Ye

Title: Ding-Yi Ye: Patent Innovation in Vascular Endothelial Health.

Introduction

Ding-Yi Ye is an inventor associated with Xi’an Jiaotong University in Xi’an, China. His patent work includes a composition intended to support the function of aortic endothelial cells and protect them from damage associated with saturated fatty acids.

Latest Patents

Ye is listed as an inventor on 1 patent: “Composition for Improving Function of Aortic Endothelial Cell and Use Thereof.” The disclosure describes a composition containing acetic acid, lactic acid, polyoxyethylene castor oil, and disodium alkyl polyoxyethylene sulfosuccinate.

The patent describes the composition as inhibiting saturated-fatty-acid-induced inflammatory responses in human aortic endothelial cells and supporting mitochondrial respiration and metabolism. It also reports reductions in inflammatory markers, including interleukin-6 (IL-6) and matrix metalloproteinase-1 (MMP-1), alongside increased expression of mitochondrial complexes I and III and the metabolism-associated factor Foxo1. The proposed application is to help prevent the occurrence and progression of atherosclerosis.

Career Highlights

Ye’s documented patent activity connects his work with research into vascular endothelial function, inflammation, and mitochondrial health. His listed institutional affiliation is Xi’an Jiaotong University.

Collaborations

The patent’s listed co-inventors include Tian-Yang Zhang and Zhi-Sheng Ye.

Conclusion

Ding-Yi Ye’s patent contribution focuses on a composition designed to reduce endothelial inflammation and support mitochondrial function, reflecting an applied research interest in vascular health and atherosclerosis prevention.