This inventor holds 1 USPTO granted patent. Top assignee: Tel Aviv University. Active years: 2009.
Company Filing History:
Years Active: 2009
Title: The Innovative Contributions of Dimitri Denisov
Introduction
Dimitri Denisov is a notable inventor based in Tel Aviv, Israel. He has made significant contributions to the field of biotechnology, particularly in the area of mapping and reconstituting binding surfaces for monoclonal antibodies. His work has implications for vaccine development, especially in the fight against HIV.
Latest Patents
Denisov holds a patent titled "Mapping and reconstitution of a conformational discontinuous binding surface." This patent focuses on the structure of conformational, discontinuous binding surfaces that associate with binding molecules, specifically the epitopes of monoclonal antibodies (mAbs). The invention involves selecting specific peptides from a peptide library to create a binding surface database. A novel computer algorithm is applied to analyze the crystalline structure of the original binding surface, allowing for the reconstitution of antigenic epitope-mimetics recognized by their original mAbs. This work is crucial for developing vaccines aimed at preventing or treating HIV.
Career Highlights
Denisov is affiliated with Ramot at Tel Aviv University Ltd., where he continues to advance his research and innovations. His expertise in the field has led to groundbreaking discoveries that enhance our understanding of antibody interactions and their applications in medicine.
Collaborations
Some of his notable coworkers include Jonathan M Gershoni and Erez Moshe Bublil. Their collaborative efforts contribute to the ongoing research and development in the field of biotechnology.
Conclusion
Dimitri Denisov's innovative work in mapping binding surfaces has the potential to significantly impact vaccine development and therapeutic strategies against diseases like HIV. His contributions exemplify the importance of research and collaboration in advancing medical science.