Dihua Shangguan

Title: Dihua Shangguan: Innovator in Aptamer Technology

Introduction

Dihua Shangguan is a prominent inventor based in Beijing, China. He has made significant contributions to the field of biotechnology, particularly in the application of aptamers for tumor detection.

Latest Patents

Dihua Shangguan holds a patent titled "Application of aptamer in recognition and binding of alkaline phosphatase heterodimer or tumor detection." This invention discloses the use of aptamers in recognizing and binding to alkaline phosphatase heterodimers. The patent provides an aptamer or its derivative, with the nucleotide sequence detailed in SEQ ID NO: 1. It also includes a kit that features an aptamer or its derivative, along with a carrier for fixing or coupling the aptamer. The method developed for capturing and detecting circulating tumor cells, exosomes, and free alkaline phosphatase in peripheral blood is based on aptamer magnetic nanoparticle technology. This innovative approach allows for highly selective capture and detection of target cells, exosomes, or free proteins.

Career Highlights

Dihua Shangguan is affiliated with the Chinese Academy of Sciences, where he continues to advance research in his field. His work has garnered attention for its potential applications in medical diagnostics and therapeutic interventions.

Collaborations

Dihua has collaborated with notable colleagues, including Tao Bing and Luyao Shen, contributing to the advancement of research in aptamer technology.

Conclusion

Dihua Shangguan's innovative work in aptamer technology represents a significant advancement in the field of biotechnology. His contributions have the potential to enhance tumor detection methods and improve patient outcomes.