Company Filing History:
Years Active: 1998-1999
Title: The Innovative Contributions of Didier Loetscher
Introduction
Didier Loetscher is a notable inventor based in Leuk-Stadt, Switzerland. He has made significant contributions to the field of pharmaceuticals, particularly in the synthesis of active ingredients. With a total of 2 patents to his name, Loetscher's work is recognized for its impact on drug development.
Latest Patents
Loetscher's latest patents focus on the process for the preparation of 1-acyl-4-arylpiperidines. These compounds are characterized by a general formula where R¹ is an aryl group that may be substituted by various alkyl and alkoxy groups, as well as fluorine atoms. R² can be a C₁-₆ alkyl group, an optionally substituted aryl group, or a benzyloxy group. The synthesis involves reacting an arylmagnesium halide with a 1-acylpyridinium halide in the presence of a copper compound, leading to the formation of 1-acyl-4-aryl-1,4-dihydropyridine, which is then hydrogenated. These 1-acyl-4-arylpiperidines serve as intermediates in the synthesis of pharmaceutical active ingredients, including neurokinin receptor antagonists.
Career Highlights
Didier Loetscher is currently associated with Lonza AG, a leading global provider of integrated healthcare solutions. His work at Lonza AG has allowed him to focus on innovative pharmaceutical processes that contribute to the development of new therapies.
Collaborations
Loetscher has collaborated with notable colleagues such as Walter Brieden and Andrew Brian Naughton. These partnerships have fostered a collaborative environment that enhances the innovation process within the pharmaceutical industry.
Conclusion
Didier Loetscher's contributions to the field of pharmaceuticals through his innovative patents and collaborations highlight his role as a significant inventor. His work continues to influence the development of important therapeutic agents.