This inventor holds 3 USPTO granted patents and 1 published patent application. Top assignees: Enzo Biochem, Inc., Enzo Therapeutics, Inc., University of Connecticut. Active years: 2013-2015.
Company Filing History:
1 out of 81 
1 out of 31 
1 out of 780 
Years Active: 2013-2015
Title: Innovations in Bone Formation: The Contributions of Dianqing (Dan) Wu
Introduction
Dianqing (Dan) Wu is an accomplished inventor based in Cheshire, CT (US). He has made significant contributions to the field of bone formation and modeling through his innovative research and patents. With a total of 3 patents, Wu's work focuses on understanding and manipulating the biological pathways involved in bone health.
Latest Patents
Wu's latest patents include groundbreaking methods for identifying compounds that interact with protein receptors involved in bone formation. One notable patent discusses compositions and methods for bone formation and modeling. This disclosure outlines methods for identifying compounds that regulate the Wnt pathway in cells by binding to specific protein receptors such as LRP5, LRP6, and frizzled receptors. These methods aim to develop treatments for diseases where Wnt pathway suppression is a factor. Another significant patent addresses the role of sclerostin in inhibiting WNT signaling and its impact on bone formation. Wu's research indicates that the loss of the SOST gene product, sclerostin, leads to high bone mass conditions. His findings reveal that sclerostin can antagonize canonical Wnt signaling, and this antagonism can be reversed by over-expressing Wnt coreceptor LRP5.
Career Highlights
Throughout his career, Wu has worked with esteemed organizations such as the University of Connecticut and Enzo Biochem, Inc. His research has contributed to a deeper understanding of the molecular mechanisms that regulate bone health and disease.
Collaborations
Wu has collaborated with notable colleagues, including Dakai Liu and James J Donegan. These partnerships have further enhanced the impact of his research in the scientific community.
Conclusion
Dianqing (Dan) Wu's innovative work in the field of bone formation has led to significant advancements in understanding the biological processes involved in bone health. His contributions through patents and research continue to influence the development of potential treatments for bone-related diseases.