Diane R Mould

Title: Innovations in Patient-Specific Dosing by Diane R Mould

Introduction

Diane R Mould is a prominent inventor based in Fort Myers, FL (US), known for her significant contributions to the field of personalized medicine. With a total of 7 patents to her name, she has focused on developing systems and methods that enhance patient-specific dosing of pharmaceuticals.

Latest Patents

One of her latest patents is titled "Systems and methods for patient-specific dosing." This innovation relates to determining a personalized dose of a pharmaceutical for an individual. The process begins with receiving first data that represents one or more characteristics of the individual prior to the administration of the pharmaceutical. Following this, second data is collected, which represents a measurement of a physiological parameter of the individual after the pharmaceutical has been administered. A computational model that includes pharmacokinetic and pharmacodynamic components is then utilized to generate a first target concentration and one or more first doses that are likely to achieve this concentration. The model is subsequently updated to reflect the physiological measurement, allowing for the generation of a second target concentration and corresponding doses that are expected to have a therapeutic effect on the individual.

Another notable patent is "System and method for providing patient-specific dosing as a function of mathematical models updated to account for an observed patient response." This system predicts and evaluates suitable medication dosing regimens tailored to individual characteristics and observed responses. It employs mathematical models of patient responses to determine an initial dose and refines the model based on the patient's observed response to enhance the accuracy of future dosing regimens. Techniques such as Bayesian averaging, updating, and forecasting are employed to develop these patient-specific dosing regimens.

Career Highlights

Throughout her career, Diane R Mould has worked with various organizations, including The Medicines Company. Her work has significantly impacted the field of personalized medicine, particularly in optimizing medication dosing for individual patients.

Collaborations

Diane has collaborated with notable professionals in her field, including Lisa Ruderman Chen and Simona Skerjanec. These collaborations have contributed to the advancement of her innovative approaches in patient-specific dosing.

Conclusion

Diane R Mould's work in developing systems for personalized medication dosing represents a significant advancement in the field of pharmaceuticals. Her innovative patents and collaborative efforts continue to pave the way for more effective and tailored treatment options for patients.