Company Filing History:
Years Active: 2011-2014
Title: **Celebrating the Innovations of Diane M Maguire**
Introduction
Diane M Maguire is a renowned inventor based in Downingtown, PA, known for her significant contributions to the field of biomedical research. With a remarkable portfolio that includes six patents, Diane has devoted her career to advancing medical treatments through innovative methodologies. Her groundbreaking work in matrix metalloproteinases highlights her commitment to improving patient outcomes.
Latest Patents
Diane's latest patents revolve around methods of treatment utilizing allosteric processing inhibitors for matrix metalloproteinases. This innovative invention encompasses a crystal structure comprising a complex of the pro form of a matrix metalloprotease (proMMP) and a small-molecule allosteric processing inhibitor. These inhibitors are pivotal as they function to inhibit the activation of proMMP, primarily proMMP9. The patents detail methods for identifying these small-molecule inhibitors and utilize the advanced crystal structure to aid in designing and optimizing inhibitors, providing a pathway for treating diseases linked to inappropriate MMP activity.
Career Highlights
Throughout her career, Diane has been instrumental in pushing the boundaries of medical research. Working with Janssen Pharmaceutica NV, she has collaborated with other esteemed professionals in the field to explore the potential of allosteric processing inhibitors. Her contributions have not only led to significant patent filings but have also opened new avenues for research and treatment strategies within the medical community.
Collaborations
Diane M Maguire has worked alongside notable coworkers, including Richard Scott Alexander and Frank A Lewandowski. These collaborations have been crucial in enhancing the depth and breadth of research undertaken at Janssen Pharmaceutica NV, fostering an environment of shared knowledge and innovative problem-solving.
Conclusion
Diane M Maguire exemplifies the dedication and creativity of inventors in the medical field. Her significant patents and collaborations are a testament to her impact on healthcare innovation. As the research continues to evolve, her work paves the way for future advancements that will undoubtedly benefit countless individuals suffering from diseases governed by matrix metalloproteinase activity.