This inventor holds 1 USPTO granted patent, plus 1 CIPO patent and 1 EPO patent. Top assignee: Janssen Vaccines & Prevention B.v.. Active years: 2019.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Company Filing History:
Years Active: 2019
Title: Diana Edo-Matas: Innovator in Poliovirus Research
Introduction
Diana Edo-Matas is a prominent inventor based in Leiden, Netherlands. She has made significant contributions to the field of virology, particularly in the development of novel methods for attenuating poliovirus strains. Her innovative approach has the potential to enhance vaccine development and improve public health outcomes.
Latest Patents
Diana holds a patent for her work on Cold-adapted-viral-attenuation (CAVA) and novel attenuated poliovirus strains. The patent describes a poliovirus strain that has been attenuated using a unique method known as Cold-Adapted-Viral-Attenuation (CAVA). The resulting recombinant attenuated poliovirus, referred to as CAVA-PV, demonstrates wild-type replication at 30°C, while showing no substantial replication at 37°C. This characteristic is defined by the inability to quantify the virus during infection at this temperature through various methods, including titration, qPCR, and Electron Microscopy. CAVA-PV is genetically stable under production conditions and can serve as a backbone for producing attenuated strains with the same antigenic profile as conventional vaccines by substituting the sequence coding for the capsid of CAVA-PV with sequences from different poliovirus strains.
Career Highlights
Diana is currently employed at Janssen Vaccines & Prevention B.V., where she continues her research and development efforts in vaccine technology. Her work is crucial in the ongoing fight against poliovirus and contributes to the advancement of vaccine science.
Collaborations
Diana collaborates with notable colleagues, including Barbara Petronella Sanders and Jerome Hubertina Henricus Victor Custers. These partnerships enhance her research capabilities and foster innovation in the field.
Conclusion
Diana Edo-Matas is a key figure in the development of innovative poliovirus strains, with her patent on Cold-adapted-viral-attenuation showcasing her expertise and dedication to improving vaccine technology. Her contributions are vital for advancing public health initiatives and combating infectious diseases.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile