Di Wu

Title: Innovations of Di Wu in Acoustic Manipulation

Introduction

Di Wu is an accomplished inventor based in Pasadena, California. He has made significant contributions to the field of acoustic manipulation through his innovative research and patents. His work focuses on the development of genetically encoded actuators that enhance the sorting of cell populations.

Latest Patents

Di Wu holds a patent for "Genetically encoded actuators for acoustic manipulation." This patent discloses methods, compositions, and kits suitable for sorting a population of cells. The method involves flowing a fluid sample containing a population of cells through a microfluidic channel. The cells are designed to express gas vesicles (GVs) in a context-dependent manner. The expression of GVs increases the compressibility and reduces the density of the cells, modulating their acoustic contrast relative to the fluid in the channel. The method also includes applying ultrasound to generate acoustic standing waves, positioning pressure antinodes within the microfluidic channel.

Career Highlights

Di Wu is affiliated with the California Institute of Technology, where he conducts his research. His work has garnered attention for its potential applications in biomedical engineering and cell sorting technologies.

Collaborations

Di Wu collaborates with Mikhail G Shapiro, further enhancing the impact of his research in the field.

Conclusion

Di Wu's innovative work in genetically encoded actuators for acoustic manipulation represents a significant advancement in cell sorting technologies. His contributions continue to influence the field and pave the way for future innovations.