Company Filing History:
Years Active: 2019-2020
Title: **Innovator Spotlight: Dennis Kaetzel**
Introduction
Dennis Kaetzel, an innovative inventor based in London, GB, has made significant strides in the field of neuroscience. Recognized for his contributions to medical technologies, he holds a total of two patents that showcase his dedication to advancing treatment options for seizure disorders, including epilepsy.
Latest Patents
One of Dennis Kaetzel's latest patents focuses on the **Combined use of a vector encoding a modified receptor and its exogenous agonist in the treatment of seizures**. This inventive approach provides methods and materials for treating seizure disorders. His invention employs a vector that encodes a modified receptor, known as the 'DREADD' receptor. This receptor is characterized by two key features: (i) a decreased responsiveness to its endogenous activating ligand and (ii) a retained or enhanced responsiveness to an exogenous agonist. By expressing this modified receptor in neurons within the seizure focus of a patient’s brain, the exogenous agonist can activate the receptor, thereby reversibly altering the excitability of these neurons. This leads to synaptic silencing or other forms of inhibition, offering a promising avenue for treating epilepsy.
Career Highlights
Dennis is currently engaged with UCL Business Plc, where he collaborates with other talented professionals in the field. Over the course of his career, his work has not only contributed to the scientific community but has also paved the way for groundbreaking clinical applications.
Collaborations
Throughout his tenure at UCL Business Plc, Dennis has had the opportunity to work alongside esteemed coworkers, including Matthew Charles Walker and Stephanie Schorge. These collaborations have further enriched his research and extended the impact of his inventions.
Conclusion
Dennis Kaetzel stands out as a notable inventor in the realm of neuroscience. With his innovative patents targeting seizure disorders, he continues to contribute significantly to the medical field, embodying the spirit of innovation and collaboration necessary for advancing healthcare solutions. His work not only showcases his expertise but also promises to enhance treatment methodologies for patients suffering from epilepsy and similar disorders.