Company Filing History:
Years Active: 2006
Title: Denise M O'Donoghue: Innovator in Pharmaceutical Development
Introduction
Denise M O'Donoghue is a distinguished inventor residing in Hightstown, NJ, USA. She has made significant strides in the field of pharmaceuticals, particularly in the development of innovative dosage forms for various medications.
Latest Patents
Denise holds a patent for "Sustained release beadlets containing stavudine." This patent describes extended dosage forms of stavudine, which are comprised of beadlets formed through a process known as extrusion-spheronization and coated with a seal coating. The innovative design enables hard gelatin capsules containing these beadlets to provide blood levels of stavudine over an extended period of approximately 24 hours. The formulation includes a dry blend of stavudine, a spheronizing agent, a suitable diluent, and a stabilizing amount of magnesium stearate. Notably, magnesium stearate enhances the stability of stavudine against hydrolysis, making it a vital component of this invention. The patent also encompasses hard gelatin capsules that may contain beadlets with other therapeutic agents aimed at treating retroviral infections.
Career Highlights
Denise has dedicated her career to advancing pharmaceutical science, working for Bristol-Myers Squibb Company. Her innovative work on sustained release formulations exemplifies her commitment to improving medication efficacy and patient outcomes.
Collaborations
Throughout her career, Denise has collaborated with esteemed colleagues, including Robert Abramowitz and Nemichand B Jain. These partnerships have played a crucial role in shaping her inventive contributions and have furthered research in the field.
Conclusion
Denise M O'Donoghue's work in developing advanced pharmaceutical formulations underscores her importance as an inventor. Her innovative approach to sustained release dosage forms continues to impact the treatment of retroviral infections, showcasing the vital role of inventors in the evolution of healthcare solutions.