Cambridge, MA, United States of America

Demetrios Kalaitzidis

This inventor holds 26 USPTO granted patents and 15 published patent applications and 1 EPO patent, primarily in Cell Engineering. Top assignee: Crispr Therapeutics Ag. Active years: 2020-2026.

IDiyas Innovation Intelligence. (2026). Inventor Profile: Demetrios Kalaitzidis. Retrieved from https://idiyas.com/inventor/demetrios-kalaitzidis

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

USPTO Granted Patents = 26 

% Patents Active = 96.2

 

Average Co-Inventor Count = 3.2

ph-index = 6

Forward Citations = 71(Granted Patents)


Company Filing History:


Years Active: 2020-2026

Loading Chart...
Loading Chart...
Areas of Expertise:
CAR-T Cells
Cancer Treatment
Cell Engineering
Immuno-Oncology
Chimeric Antigen Receptors
Genetically Engineered T Cells
Persistence
Allogeneic Cell Therapy
Regnase-1
TGFBRII Disruption
B Cell Malignancies
Manufacturing Process
26 patents (USPTO):Explore Patents

Title: Demetrios Kalaitzidis: Innovator in Cancer Treatment

Introduction: Demetrios Kalaitzidis, a prominent inventor based in Cambridge, MA, has made significant contributions to the field of cancer research. With an impressive portfolio of 22 patents, Kalaitzidis has been at the forefront of developing innovative methods and compositions for cancer treatment. His groundbreaking work at Crispr Therapeutics AG has notably advanced genetic engineering techniques used in immunotherapy.

Latest Patents: Among his recent patents, one of the most notable focuses on methods and compositions for treating cancer. This invention encompasses a population of genetically engineered T cells featuring disruptions in the Regnase-1 and/or TGFBRII genes. The engineered T cells demonstrate several advantages, including enhanced cell growth activity, improved persistence, and increased cytotoxicity. These advancements hold promise for overcoming inhibitory effects typically faced by non-engineered T cells in the treatment of cancer.

Career Highlights: Kalaitzidis has had a distinguished career marked by his innovative approaches to cancer therapy. His expertise in genetic engineering has not only led to the development of novel treatment modalities but has also garnered recognition within the scientific community for his impactful research contributions. Working at Crispr Therapeutics AG, he plays a critical role in spearheading initiatives that blend cutting-edge technology with medical applications.

Collaborations: Throughout his career, Kalaitzidis has collaborated with notable colleagues, including Jonathan Alexander Terrett and Lawrence Klein. These partnerships have been instrumental in enhancing research outcomes and fostering an environment of shared knowledge and innovation. Together, they continue to explore new frontiers in cancer treatment through collaborative efforts in their respective fields.

Conclusion: Demetrios Kalaitzidis exemplifies the spirit of innovation in the realm of cancer research. With a rich background in patents and groundbreaking inventions, his work has the potential to transform therapeutic approaches for cancer patients. Through his contributions at Crispr Therapeutics AG and collaborations with esteemed colleagues, Kalaitzidis is undoubtedly a pivotal figure in the pursuit of effective cancer treatments.

Profile summary based on public USPTO records.
Data Sources: USPTO Patent Grant XML, Patent Center, EPO & CIPO • Normalized by IDiyas Innovation Graph. Methodology & provenance architecturePlease report any incorrect information to [email protected]
Loading…