Delphine Gulligay

Title: Delphine Gulligay: Innovator in Influenza Virus Research

Introduction

Delphine Gulligay is a prominent inventor based in Voreppe, France. She has made significant contributions to the field of virology, particularly in the study of influenza viruses. Her innovative work has led to the development of a patent that addresses critical aspects of viral infections.

Latest Patents

Delphine Gulligay holds a patent for "Soluble fragments of influenza virus PB2 protein capable of binding RNA-cap." This invention relates to soluble fragments of the Influenza virus RNA-dependent RNA polymerase subunit PB2 and variants thereof. It also includes crystallized complexes comprising an RNA cap analog. The invention provides computational methods using the structural coordinates of the complex to screen for and design compounds that interact with the RNA cap binding pocket. Furthermore, it outlines methods for identifying compounds that bind to PB2 polypeptide fragments, preferably inhibiting the interaction with RNA caps or analogs. This work is crucial for developing compounds and pharmaceutical compositions aimed at treating diseases caused by negative-sense single-stranded RNA viruses.

Career Highlights

Delphine Gulligay is affiliated with the European Molecular Biology Laboratory, where she continues her research and development efforts. Her work has garnered attention for its potential impact on public health and the treatment of viral infections.

Collaborations

Throughout her career, Delphine has collaborated with notable scientists, including Stephen Cusack and Darren James Hart. These collaborations have enriched her research and contributed to the advancement of knowledge in her field.

Conclusion

Delphine Gulligay is a trailblazer in the realm of influenza virus research, with a patent that showcases her innovative approach to combating viral infections. Her contributions are vital for the ongoing fight against diseases caused by RNA viruses.