Deirdre McIntosh

Title: Deirdre McIntosh: Innovator in Lipidic Compositions for Oligodeoxynucleotide Delivery

Introduction

Deirdre McIntosh is a prominent inventor based in Vancouver, Canada. She has made significant contributions to the field of lipidic compositions, particularly in the delivery of oligodeoxynucleotides (ODN). Her innovative work has the potential to enhance therapeutic applications in biotechnology and medicine.

Latest Patents

Deirdre McIntosh holds a patent for a composition containing small multilamellar oligodeoxynucleotide-containing lipid vesicles. This invention focuses on lipidic compositions with superior characteristics for in vivo delivery of oligodeoxynucleotides. The compositions consist of a population of nucleic acid-containing lipid vesicles in a liquid carrier, with at least a portion being small multilamellar vesicles. These vesicles are created using a lipid component that includes 20-30 mol % of an ionizable amino lipid, such as DODAP, along with a steric barrier lipid like PEG-CerC. The oligodeoxynucleotide is contained within the vesicles, which are produced through a specific preparation process involving lipid and aqueous solutions.

Career Highlights

Deirdre McIntosh is affiliated with the University of British Columbia, where she continues her research and development in lipidic compositions. Her work has garnered attention for its innovative approach to drug delivery systems, particularly in the context of genetic therapies.

Collaborations

Some of her notable coworkers include Sean C Semple and Sandra K Klimuk, who have collaborated with her on various research projects related to lipidic compositions and their applications.

Conclusion

Deirdre McIntosh's contributions to the field of lipidic compositions for oligodeoxynucleotide delivery represent a significant advancement in biotechnology. Her innovative patent and ongoing research at the University of British Columbia highlight her role as a leading inventor in this important area.