Company Filing History:
Years Active: 1990
Title: Deborah G Grenzowski: Innovator in Cell Culture Technology
Introduction
Deborah G Grenzowski is a notable inventor based in Nepean, Canada. She has made significant contributions to the field of biotechnology, particularly in the development of cell culture technologies. Her innovative work has led to the creation of a unique apparatus that enhances the efficiency of cell culture processes.
Latest Patents
Deborah holds a patent for a cell culture bioreactor. This invention is particularly suitable for the culture of viable, shear-sensitive cells, whether grown in suspension or attached to substrates like microcarrier beads. The apparatus features a cell culture compartment and a compensation chamber above it, which helps maintain sterile conditions while operating in a zero-headspace mode. The design includes a gas exchange tube connected to an external gas source, creating both a downflow and a central upflow zone within the culture compartment. An Archimedean screw-type auger is installed to facilitate a circulating flow of liquid, while upper and lower flow guide surfaces reduce turbulence. The gas exchange tube is designed to enhance gas exchange efficiency by interacting with both the outer and inner surfaces of the liquid inside the culture compartment.
Career Highlights
Deborah has worked with Canadian Patents & Development Ltd., where she has applied her expertise in biotechnology to advance innovative solutions in cell culture technology. Her work has been instrumental in improving the conditions for growing sensitive cell types, which is crucial for various applications in research and medicine.
Collaborations
Throughout her career, Deborah has collaborated with notable colleagues, including David W Armstrong and L Perry Fleming. These partnerships have contributed to the development and refinement of her innovative technologies.
Conclusion
Deborah G Grenzowski is a pioneering inventor whose work in cell culture technology has made a significant impact in the field of biotechnology. Her patented inventions continue to enhance the efficiency and effectiveness of cell culture processes, showcasing her dedication to innovation and research.