Dean Staus

Title: Dean Staus: Innovator in G-Protein Coupled Receptor Research

Introduction

Dean Staus is a prominent inventor based in Durham, NC (US). He has made significant contributions to the field of biochemistry, particularly in the study of G-protein coupled receptors (GPCRs). His innovative work has implications for various medical conditions, including obstructive airway disease and bronchospasm.

Latest Patents

Dean Staus holds a patent titled "System and method for homogenous GPCR phosphorylation and identification of beta-2 adrenergic receptor positive allosteric modulators." This patent focuses on a G-protein coupled receptor complex that includes a chimeric GPCR with a non-native amino acid sequence and a synthetic phosphopeptide. The invention also describes an in vitro method for producing this complex and identifying compounds that can modulate its activity. The positive allosteric modulators identified through this research have potential applications in treating various medical conditions.

Career Highlights

Dean Staus is affiliated with Duke University, where he conducts his research. His work has garnered attention for its innovative approach to understanding GPCRs and their role in pharmacology. He has been instrumental in advancing the field through his research and patent contributions.

Collaborations

Throughout his career, Dean has collaborated with notable scientists, including Robert J Lefkowitz and Seungkirl Ahn. These collaborations have further enriched his research and expanded the impact of his work in the scientific community.

Conclusion

Dean Staus is a key figure in the field of GPCR research, with a focus on innovative methods for drug discovery. His contributions through patents and collaborations continue to influence the landscape of biochemistry and pharmacology.