Dean-Mo Liu

Title: Dean-Mo Liu: Innovator in Biofunctional Coatings and Drug Delivery Systems

Introduction

Dean-Mo Liu is a prominent inventor based in Richmond, CA (US). He has made significant contributions to the field of biofunctional coatings and drug delivery systems. With a total of 3 patents, his work focuses on innovative methods for drug encapsulation and release.

Latest Patents

One of Dean-Mo Liu's latest patents is titled "Biofunctional hydroxyapatite coatings and microspheres for in-situ drug encapsulation." This invention relates to a novel room-temperature process for obtaining calcium phosphate, particularly hydroxyapatite, coatings and microspheres that encapsulate drugs, proteins, genes, and DNA for therapeutic use. The coatings and microspheres are designed to perform a defined biological function related to drug delivery, such as gene therapy through gene delivery. A novel method for encapsulation and subsequent controlled release of therapeutically active agents from such biofunctional coatings and microspheres is disclosed. These coatings and microspheres are useful for side-effect-free, long-term, targeted, controlled release and delivery of drugs, proteins, DNA, and other therapeutic agents.

Another significant patent is "Sol-gel calcium phosphate ceramic coatings and method of making same." This invention relates to novel sol-gel calcium phosphate, particularly hydroxyapatite ceramic coatings and processes for making them at low temperatures. Such coatings are useful, inter alia, for dental implants and bone-metal contact appliances. The sol-gel process for preparing a crystallized hydroxyapatite involves hydrolyzing a phosphor precursor in a water-based medium, adding a calcium salt precursor to the medium after hydrolysis, and calcining the crystallized hydroxyapatite at a suitable elevated temperature.

Career Highlights

Dean-Mo Liu has worked at prestigious institutions, including the University of British Columbia and the University of Pennsylvania. His work has significantly impacted the fields of materials science and biomedical engineering.

Collaborations

Throughout his career, Dean-Mo Liu has collaborated with notable colleagues, including Tomasz Troczynski and I-Wei Chen. These collaborations have further advanced his research and innovations in biofunctional coatings.

Conclusion

Dean-Mo Liu is a distinguished inventor whose work in biofunctional coatings and drug delivery systems has led to significant advancements in therapeutic applications. His innovative patents reflect his commitment to improving healthcare