Company Filing History:
Years Active: 1999-2006
Title: Dean H Johnston: Innovator in Nucleic Acid Detection
Introduction
Dean H Johnston is a prominent inventor based in Columbus, OH (US). He has made significant contributions to the field of electrochemical detection of nucleic acids. With a total of 4 patents, his work has implications in various applications, including DNA sequencing and diagnostic assays.
Latest Patents
One of Johnston's latest patents is a microelectronic device for electrochemical detection of nucleic acid hybridization. This method involves detecting a nucleic acid, such as DNA or RNA, that contains at least one preselected base. The process includes reacting the nucleic acid with a transition metal complex capable of oxidizing the preselected base in an oxidation-reduction reaction. The detection of this reaction allows for the determination of the presence or absence of the nucleic acid. This innovative method can be utilized in diverse applications, including DNA sequencing, diagnostic assays, and quantitative analysis.
Career Highlights
Johnston is affiliated with the University of North Carolina at Chapel Hill, where he continues to advance research in his field. His work has garnered attention for its potential to enhance the accuracy and efficiency of nucleic acid detection methods.
Collaborations
Throughout his career, Johnston has collaborated with notable colleagues, including H Holden Thorp and Mary E Napier. These partnerships have contributed to the development and refinement of his innovative techniques.
Conclusion
Dean H Johnston's contributions to the field of nucleic acid detection exemplify the impact of innovation in scientific research. His patents and ongoing work continue to pave the way for advancements in diagnostic technologies.