Company Filing History:
Years Active: 1996-2006
Title: Innovations of Dean A. Kirby
Introduction
Dean A. Kirby is a notable inventor based in San Diego, California. He has made significant contributions to the field of biological studies, particularly through his innovative patents. With a total of two patents to his name, Kirby's work focuses on developing selective ligands and cyclic peptide analogs that have important therapeutic applications.
Latest Patents
Kirby's latest patents include the development of CRFR2 selective ligands. These CRF peptide analogs bind to CRFR2 with an affinity that is significantly greater than their binding to CRFR1. This unique property allows these analogs to exhibit CRF antagonist activity, and they can be based on the native structures of sauvagine, CRF, and urocortin. Additionally, he has developed centrally truncated NPY cyclic peptides. These analogs demonstrate selective bioactivity for NPY Y1 receptors. Methods for diagnosing physiological disorders related to abnormal levels of endogenous Y1 receptors are also provided. This includes measuring the amount of a NPY Y1 specific cyclic peptide analog that binds to a biological sample, as well as administering a radiolabelled NPY Y1 specific cyclic peptide analog for radiographic imaging. Furthermore, Kirby's work includes therapeutic applications of these cyclic peptide NPY analogs in treating conditions such as hypotension and anorexia.
Career Highlights
Kirby is affiliated with the Salk Institute for Biological Studies, where he continues to advance his research and innovations. His work has garnered attention in the scientific community, contributing to the understanding of receptor interactions and their implications in various physiological conditions.
Collaborations
Throughout his career, Kirby has collaborated with esteemed colleagues, including Jean E. Rivier and Jean E. F. Rivier. These collaborations have further enriched his research and expanded the impact of his inventions.
Conclusion
Dean A. Kirby's contributions to the field of biological studies through his innovative patents highlight his role as a significant inventor. His work on CRFR2 selective ligands and NPY cyclic peptides showcases the potential for advancements in therapeutic applications.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.