Location History:
- Malden, MA (US) (2016 - 2017)
- Boston, MA (US) (2019 - 2023)
Company Filing History:
6 out of 1,206 
2 out of 1,370 
Years Active: 2016-2025
Title: The Innovations of De-Kuan Chang
Introduction
De-Kuan Chang is a prominent inventor based in Boston, MA, known for his significant contributions to the field of biomedical research. He holds a total of six patents, showcasing his innovative approach to developing therapeutic solutions.
Latest Patents
One of his latest patents is focused on humanized CC chemokine receptor 4 (CCR4) antibodies and methods of use thereof. This invention provides humanized monoclonal antibodies, bi-specific antibodies, antibody conjugates, and fusion proteins that bind to the chemokine receptor CCR4. The antibody is derived from CCR4-IgG1 and recognizes the same epitope. It contains either an IgG4 or a stabilized IgG4 to improve binding efficiency and reduce in vivo Fab arm exchange. The binding of these antibodies to CCR4 inhibits ligand-mediated activities and is utilized to treat symptoms of cancer.
Career Highlights
Throughout his career, De-Kuan Chang has worked with esteemed institutions such as Dana-Farber Cancer Institute Inc. and Brigham and Women's Hospital, Inc. His work has significantly impacted cancer research and treatment methodologies.
Collaborations
De-Kuan Chang has collaborated with notable colleagues, including Wayne A. Marasco and Quan Zhu, further enhancing the scope and impact of his research.
Conclusion
De-Kuan Chang's innovative work in developing humanized antibodies represents a significant advancement in cancer treatment. His contributions continue to influence the biomedical field and offer hope for improved therapeutic options.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.