Palo Alto, CA, United States of America

David Wade


Average Co-Inventor Count = 3.3

ph-index = 2

Forward Citations = 9(Granted Patents)


Company Filing History:


Years Active: 2004-2008

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3 patents (USPTO):Explore Patents

Title: David Wade: Innovator in Cholesterol Efflux Research

Introduction

David Wade is a prominent inventor based in Palo Alto, CA (US). He has made significant contributions to the field of biochemistry, particularly in the area of cholesterol metabolism. With a total of 3 patents to his name, Wade's work focuses on innovative methods to enhance cholesterol efflux and raise HDL levels.

Latest Patents

Wade's latest patents include compositions and methods for increasing cholesterol efflux and raising HDL using ATP binding cassette transporter protein ABC1. This invention relates to novel ABC1 polypeptides and nucleic acid molecules encoding the same. It also encompasses recombinant vectors, host cells, and compositions comprising ABC1 polynucleotides, as well as methods for producing ABC1 polypeptides. Furthermore, the invention includes antibodies that bind specifically to ABC1 polypeptides. In addition, it outlines methods for increasing cholesterol efflux and enhancing ABC1 expression and activity. The present invention also provides methods for identifying compounds that modulate the expression of ABC1 and for detecting the comparative level of ABC1 polypeptides and polynucleotides in a mammalian subject. Moreover, it offers kits and compositions suitable for screening compounds to determine their ABC1 expression modulating activity, as well as those suitable for assessing whether a compound modulates ABC1-dependent cholesterol efflux.

Career Highlights

David Wade is currently associated with Cv Therapeutics, Inc., where he continues to advance his research in cholesterol metabolism. His work has been instrumental in developing new therapeutic strategies aimed at improving cardiovascular health.

Collaborations

Wade has collaborated with notable colleagues, including Richard M Lawn and Michael Garvin, who have contributed to his research endeavors.

Conclusion

David Wade's innovative work in cholesterol efflux research has the potential to significantly impact cardiovascular health. His contributions through patents and collaborations highlight his role as a leading inventor in this vital field.

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